Encapsulated Streptococcus Compositions and Methods for Pneumococcal Vaccine,...
Streptococcus pneumoniae (S. pneumoniae) bacteria, or pneumococcus, can cause many types of illnesses. These range from ear and sinus infections to life-threatening conditions such as pneumonia,...
View ArticleMonoclonal Antibody to Detect the Antiretroviral Drug Emtricitabine – for HIV...
The U.S. Food and Drug Administration and World Health Organization (WHO) approved the antiretroviral drug emtricitabine (FTC)/ tenofovir disoproxil fumurate (TDF) combination for HIV pre-exposure...
View ArticleOne-step random amplification method to detect extremely low input nucleic...
Clinical and biological specimens often contain microbial nucleic acid in extremely low quantities, presenting a significant challenge for the detection of viral and bacterial pathogens. This also...
View ArticleCDC Mosquito Trap for Control and Surveillance of Mosquitoes Including...
Mosquitoes are responsible for spreading many viruses that can make people sick, including dengue, Zika, chikungunya, yellow fever, and more. The Centers for Disease Control and Prevention's (CDC's)...
View ArticleReal-Time RT-PCR Detection of Scrub Typhus Total Nucleic Acid Assay with High...
Scrub typhus is a bacterial disease caused by Orientia tsutsugamushi (O. tsutsugamushi or Ots) that is spread to people through bites of infected chiggers (larval mites). The most common symptoms can...
View ArticleReal-Time RT-PCR Detection of Rickettsia species -- PanR6/Total Nucleic Acid...
Rickettsial infections are caused by bacteria from the Rickettsia genus which are often spread by biting ticks, fleas, mites or lice. Rickettsia can cause mild to severe illness and Rickettsia species...
View ArticlePhotoinduced Electron Transfer Fluorescent Primer for Nucleic Acid Amplification
CDC scientists have developed a rapid and cost-efficient method for generating fluorescently labeled primers for PCR and real-time PCR. At present, fluorescent primers are useful for detecting and...
View ArticleMonitoring Public Water Supply for a Variety of Pathogens
The simultaneous concentration and recovery of microbes in drinking water is important for responding to potential water-related events such as pathogen contamination or bioterrorism and could be a...
View ArticleFluorescent Primer(s) Creation for Nucleic Acid Detection and Amplification
CDC researchers have developed technology that consists of a simple and inexpensive technique for creating fluorescent labeled primers for nucleic acid amplification. Fluorescent chemical-labeled...
View ArticleUniversal Influenza Virus Probes for Enrichment of Influenza Viral Sequences
This technology is a set of influenza virus enrichment probes developed to increase the sensitivity of sequence-based, universal detection of all influenza viruses. This universal influenza enrichment...
View ArticleNovel One-Well Limiting-Antigen Avidity Enzyme Immunoassay to Detect Recent...
This CDC developed Limiting-Antigen avidity Enzyme Immunoassay (LAg-avidity-EIA) provides an easy way to measure increasing binding strength (avidity) of HIV antibodies as part of maturation HIV...
View ArticleSimian T-Cell Lymphotropic Virus Strain Type 3 (STLV-3) Subtype D Variant, a...
Simian T-cell lymphotropic viruses (STLV) are nonhuman primate retroviruses closely related to the human T-lymphotropic virus (HTLV). Types I, II, and III of HTLV have been found in humans and are...
View ArticleStable Human Cell Lines Expressing Flavivirus Virus-Like Particles (VLPs) for...
Flaviviruses such as Zika virus, dengue virus, West Nile virus, yellow fever virus, and Japanese encephalitis virus cause widespread illness and death throughout the world. Typically, flaviviruses get...
View ArticleMonoclonal Antibodies Against Coxiella burnetii, the Cause of Q Fever for...
Coxiella burnetii (C. burnetii), the bacterium that causes Q fever, gets transmitted by inhalation and remains extremely stable in the environment. It has a very low infectious dose (very few bacteria...
View ArticleMonoclonal Antibodies for Detection of Rabies Virus Antigen and Confirmatory...
According to the World Health Organization (WHO), rabies causes greater than 59,000 deaths every year in over 150 countries as of 2017. A rapid and reliable diagnostic test for rabies is critical for...
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